(I'm posting this because I just took 3 hours of my life finding the solution.)
On two computers...Outlook would start, but then peg the processor to 100% (50% on the dual core machine). After a few minutes, the processor usage would go down...but if I tried to use the menus it would go back up to 100%. I was able to start Outlook in Safe Mode, but that didn't help since we need a few Outlook Add-ins. I tried repairing office, reinstalling office and uninstalling anything I could think of that might interfere (iTunes, Skype, Symantec Antivirus, Adobe Acrobat) but nothing worked.
I decided to look at the Outlook Command Line Reference and noticed the "/nocustomize" option; "Starts Outlook without loading outcmd.dat (customized toolbars) and *.fav file." With that option, Outlook started and worked fine (with my add-ins loaded). I closed Outlook, searched my computer for outcmd.dat, deleted the two copies it found, started Outlook. The two users that were having the issue are now back working, and I am a happy man!
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